Indiana University School of Medicine
Department of Medical and Molecular Genetics
Center for Computational Biology and Bioinformatics
Human Evolutionary and Statistical Genetics Lab
The Human Evolutionary and Statistical Genetics (HESG) Lab develops computational and statistical methods that leverage human genetic diversity, population history, and evolutionary processes to uncover the genetic basis of complex traits and diseases.
Principal Investigator
Kai Yuan, PhD
Assistant Professor in the Department of Medical and Molecular Genetics at the Indiana University School of Medicine and the Center for Computational Biology and Bioinformatics.
I am interested in understanding how human evolutionary history shapes genetic variation and influences complex diseases. My research sits at the intersection of evolutionary genetics, population genetics, and statistical genetics, with a particular focus on developing computational methods that leverage human genetic diversity for genetic discovery.
At the HESG Lab, we develop innovative approaches for fine-mapping, genetic association studies, and population genetic inference. Our goal is to connect population history with disease biology and transform genetic diversity into a powerful tool for understanding human health and disease.